Methodology
To this end, the following specific objectives will be pursued:
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Objective 1: Construction of epilepsy-specific deep TMS coils in spherical models.
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Objective 2: Optimization and validation of the epilepsy-specific deep TMS coils in anatomical models.
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Objective 3: Development, testing and validation in healthy volunteers of deep TMS-EEG stimulation and analysis protocols.
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Objective 4: Diagnostic validation of deep-TMS-EEG biomarkers in epilepsy.
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Objective 5: Therapeutic validation of deep-TMS-EEG in epilepsy.