Thessaloniki Software Solutions S.A. (THESS) was founded in 2011 as a small company with the mission of using information and communication technology (ICT) for the improvement of the quality of life. To this direction THESS focuses on the development and marketing of innovative software and hardware solutions for biomedical, telecommunication and scientific applications. However, it is also ready to address the ICT needs of customers with special requirements about web services and mobile terminal applications.
Furthermore, the company is specialized in services in the field of computational life sciences with vast experience in numerical simulations for modeling physiological processes, ranging from neurophysiological stimulation to bioheat transfer. The creation of numerical (digital) models for computer calculations is another business area of THESS.
The staff of THESS has a strong scientific background in the area of computational and applied electromagnetics, especially in the interaction of human tissues with radiofrequency radiation either for medical or for safety and compatibility (EMC/EMI) purposes. Its personnel has been involved in a number of projects at a national and European level ranging from the evaluation of human exposure to non-ionizing electromagnetic radiation to the quality assessment measurements of wireless and optical fiber networks.

AUTH has intense research activity in the field of brain stimulation in epilepsy and collaborates on this issue with international centers of excellence, including the Kuopio University Hospital (Finland), Kings College London (London, UK), Universidad Complutense Madrid (Madrid, Spain), Hospices Civils de Lyon (Lyon, France) and CHUV (Lausanne, Switzerland).
The AUTH group comprises 3 collaborating laboratories with the following research profiles:
1)The Laboratory of Clinical Neurophysiology of the Aristotle University of Thessaloniki is located at the AHEPA University Hospital and is participating in a European pilot network of reference centers in refractory epilepsy and epilepsy surgery (E-Pilepsy project in the framework of the Health Programme, 2008–2013). The Laboratory has applied and developed, over the last 20 years, a number of TMS-EMG and TMS-EEG techniques in the investigation of the human CNS in health and disease with an emphasis on the pathophysiological mechanisms of Epilepsy and the impact of AEDs. The group has developed novel, internationally acknowledged TMS approaches for investigating the cortical inhibitory phenomenon of silent period and has explored extensively the effect of TMS on epileptiform discharges and effective connectivity in partial and Genetic Generalized epilepsies.
2) The EEG Analysis group has considerable experience in EEG analysis and is active in developing methods of time-series analysis with emphasis on nonlinear dynamics and complexity. The group currently develops techniques in the fields of connectivity analysis, complex networks, feature-based classification, all of which are applied to EEG. The EEG Analysis group is connected to the Informatics Laboratory, which is active among others in the areas of information security and Health care informatics (e-health).
3)The NeuroInformatics group of AIIA laboratory employs graph-theoretic, data-mining, machine learning and visualization techniques for understanding the real time processing in the brain. The group has recently developed a set of novel methodologies for extracting semantics from multichannel recordings, tracking functional connectomics, and learning distinctive dynamic characteristics from brain responses.

Brain R&D

Boston children’s Hospital / Harvard Medical School, Neuromodulation Program under Prof. Alexander Rotenberg.